ROLE OF ENZYMATIC ACTIVITY IN MUSCLE DAMAGE AND CYTOTOXICITY INDUCED BY BOTHROPS ASPER ASP49 PHOSPHOLIPASE A2 MYOTOXINS: ARE THERE ADDITIONAL EFFECTOR MECHANISMS INVOLVED?

Viperid venoms often contain mixtures of Asp49 and Lys49 PLA2 myotoxin isoforms, relevant to development of myonecrosis.Given their difference in catalytic activity, mechanistic studies on each type require highly purified samples.Studies on Asp49 PLA2s have shown that enzyme inactivation using p-bromophenacyl bromide (p-BPB) drastically affects to

In the present research, the selective oxidation of lauryl alcohol to lauraldehyde was studied under liquid-liquid phase transfer conditions using potassium chromate (K2CrO4) as an oxidizing agent and tetrabutyl ammonium bromide (TBAB) as the phase transfer catalyst.Chromium (VI) reagents are used in these oxidations since the alcohols are selectiv

In order to effectively improve the safety and reliability of electric locomotives in the driving process, the research on electric locomotive failure prediction and health management technology was carried out and an overall system plan was formed, which realized the Kits health management of intelligent monitoring and fault prediction of the impo

If the origin of life is rare and sensitive to the local conditions at the site of its emergence, then, using the principle of mediocrity within a multiverse framework, we may expect to find ourselves in a universe that is better Supplements for Men than usual at creating these necessary conditions.We use this reasoning to investigate several origi